![]() ![]() It develops sporadically and is independent of celiac disease. EATL type II is mainly composed of small to medium-sized cells, which show positivity for CD3, CD7, CD8, and CD56. The other type, namely EATL type II, comprises 10% to 20% of all EATL cases. In this type, tumor cells are large and pleomorphic and positive for CD3 and CD7 in immunohistochemistry staining, but negative for CD4, CD8, or CD56. 1 The classic EATL, also known as EATL type I, is predominantly found in Western countries and is strongly associated with refractory celiac disease. It is known to arise from T lymphocytes that reside in the intraepithelial space of the intestines and is classified into two types. Here, we present the clinical and endoscopic findings of four cases of EATL type II diagnosed by endoscopy.Įnteropathy-associated T-cell lymphoma (EATL) is a rare intestinal tumor, accounting for less than 5% of gastrointestinal lymphoma. There are only few published reports regarding the representative endoscopic findings of EATL. In contrast, the endoscopic findings of the colon were nonspecific and could not distinguish EATL type II from other diseases. Common endoscopic findings included innumerable fine granularities (also called mosaic mucosal patterns) and diffuse thickening of the mucosa with a semicircular shallow ulceration in the lesions of the small bowel. Among the four patients, two of the cases involved both the small and large intestines, whereas in the other two patients, EATL was limited to the small intestine. Four of the five patients were diagnosed with the help of endoscopy. A total of five cases of EATL type II were diagnosed at our clinic from January 2009 to September 2012. In contrast to the classic EATL type I, EATL type II occurs sporadically, is unrelated to celiac disease, and comprises 10% to 20 % of all EATL cases. Enteropathy-associated T-cell lymphoma (EATL) is a rare extranodal T-cell lymphoma arising from the intestine. ![]()
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